Krystal Thomas had a double-double of 14 points and 13 rebounds, leading four Duke players in double figures as the No. 5 Blue Devils smacked host James Madison 75-58.
Dawn Evans had 20 points for the losing Dukes, while Lauren Jimenez added 19 points and 11 rebounds.
Duke, which led 43-32 at halftime, shot 46.9 percent to 36.4 for the hosts and outrebounded them 39-30.
The finale of the Blue Devils’ four-game road trip is on Thursday night at Wisconsin in the ACC/Big Ten Challenge. Duke hosts No. 7 Texas A&M in the Jimmy V Classic on Monday night.