The Textile Bowl belongs to host Clemson by a single point, and N.C. State suddenly became a longer shot to play in the ACC Championship Game.
Facing fourth-and-one from the Clemson 43 and trailing by a point with just under four minutes left, the Wolfpack decided to punt.
State got the ball back at its own 14 with 2:56 to play, but was able to move only 14 yards.
The Wolfpack led 10-0 midway through the third quarter after a Russell Wilson touchdown pass to Mustafa Greene and a Josh Czajkowski field goal.
Clemson cut it to 10-7 with 3:00 left in the third on a 12-yard pass from Kyle Parker to DeAndre Hopkins.
After Czajkowski nailed a 27-yard field goal with 13:25 left, the Tigers came up with the winner.
Wilson completed 22 of 36 passes for 216 yards and the touchdown with one interception.
Parker was 22-for-30 for 218 yards and the touchdown with one interception.