Duke has had three days to lick its wounds after its 33-point home-court loss to No. 1 Connecticut.
Tonight, the No. 6 Blue Devils (15-3, 3-0 ACC) return to the ACC women's basketball wars.
The visitor to Cameron Indoor Stadium will be Virginia Tech (11-6, 1-2), which has already slain one conference giant this season.
Beth Dunkenberger's Hokies, who were picked last in the ACC in preseason, pulled a big surprise on Thursday night, topping preseason conference favorite UNC 79-64 in Blacksburg.
A win tonight by the Hokies would be a bigger upset. Duke has won 11 straight in the series.
Jasmine Thomas (pictured), who got 17 points against the Huskies, is Duke's leading scorer.
Northern Durham alumna Utahya Drye is the Hokies' leading rebounder.
No. 6 Duke vs. Virginia Tech
[Thursday, 7 p.m., Cameron Indoor Stadium]
Duke leads series 13-2.
Records: Duke 15-3, 3-0 ACC; VT 11-6, 1-2 ACC.
Audio: WDNC-AM 620, GoDuke.com, HokieSports.com.
Coaches' records - VT: Beth Dunkenberger 160-126, 95-76 at VT; Duke: Joanne P. McCallie 382-167, 67-19 at Duke.
Leading scorers - VT: Lindsay Biggs 11.9; Duke: Jasmine Thomas 15.7.
Leading rebounders - VT: Utahya Drye 6.8; Duke: Krystal Thomas 7.5.
Assist leaders - VT: Nikki Davis 4.7; Duke: Jasmine Thomas 4.9.