N.C. State's four-game winning streak ran into a brick wall at Boston College.
Bonae Holston (pictured) led the Wolfpack with 19 points, but the Eagles got huge games out of three players to coast to an 83-66 win.
Mickel Picco had 21 points, 17 of them in the first half, to lead BC (10-6) to victory in its ACC opener.
Brittanny Johnson added a career-high 19 points for the Eagles, while center Carolyn Swords added 17 points and 16 rebounds.
Nikitta Gartrell added 15 points for State (11-6, 1-1 ACC) while Tia Bell added 15, but no other Wolfpack player scored more than five.
The Eagles dominated the boards by a 44-26 margin.
BC visits Maryland on Thursday night, while the Wolfpack's next game is Jan. 17 at Florida State.